个人简介

       杨学勇，1982年生，中国农业科学院蔬菜花卉研究所研究员，博士生导师，担任蔬菜功能基因组创新团队首席。

科研情况

       主要围绕葫芦科瓜类等作物源库互作的生物学过程，挖掘和解析关键变异、变异与基因组互作、变异与环境互作，并定向创制变异来改良作物。旨在建立广泛适用的方法论，系统地进行源、库、流的科学改造和设计，实现作物的产量、品质和环境适应性的协同提升。以通讯/第一作者在Cell、Nature Plants、The Plant Cell等重要期刊上发表SCI论文20余篇。主持了国家级、省部级项目和课题6项。获国家自然科学基金A类和B类项目资助、以及农业科研杰出人才培养计划等；担任中国园艺学会蔬菜专委会秘书长。

主要成果

1. Tongxu Xin ^#, Zhen Zhang ^#, Yueying Zhang ^#, Xutong Li ^#, Shenhao Wang, Guanqun Wang, Haoxuan Li, Bowen Wang, Mengzhuo Zhang, Wenjing Li, Haojie Tian, Zhonghua Zhang，Yu-Lan Xiao, Weixin Tang, Chuan He, Yiliang Ding^*, Sanwen Huang^*, Xueyong Yang^*. Recessive epistasis of a synonymous mutation confers cucumber domestication through epitranscriptomic regulation. Cell, 2025, https://doi.org/10.1016/j.cell.2025.06.007.
   

2. Zhaonian Dong^#, Xiaolin Liu ^#, Xing Guo^#, Xun Liu^#, Bowen Wang^#, Wenwen Shao^#, Caihuan Tian, Yingying Zheng, Qiong Yu, Liyuan Zhong, Jinjing Sun, Shengkang Li, Tongxu Xin, Bohan Zhang, Tao Yang, Haorong Lu, Jocelyn K. C. Rose, William J. Lucas, Xun Xu, Sanwen Huang, Huan Liu^*, Xueyong Yang^*. Developmental innovation of inferior ovaries and flower sex orchestrated by KNOX1 in cucurbits. Nature Plants, 2025, 11(4)：861–877.

3. Shenhao Wang ^#, Kun Wang^#, Li Zheng^#, Yangyang Li, Jiao He,Hongbo Li, Bowen Wang; Tongxu Xin; Jiaxing Tian, Guoyu Zhang; Haojie Tian, HaizhenLi, Sanwen Huang, Xueyong Yang^*. Architecture design of cucurbit crops for enhanced productivity by a natural allele, Nature Plants, 2022, 8(12): 1394-1407. 

4. Xueyong Yang^#, Jianbin Yan ^#, Zhen Zhang^#, Tao Lin, Tongxu Xin, Bowen Wang, Shenhao Wang, Jicheng Zhao, Zhonghua Zhang, William J. Lucas, Guohong Li, Sanwen Huang *. Regulation of plant architecture by a novel histone acetyltransferase targeting gene bodies. Nature Plants, 2020, 6(7): 809- 822.

5. Tongxu Xin^#, Zhen Zhang^#, Shuai Li, Shu Zhang, Qing Li, ZhongHua Zhang, Sanwen Huang, Yang Xueyong^*. Genetic Regulation of Ethylene Dosage for Cucumber Fruit Elongation, The Plant Cell, 2019, 31(5): 1063-1076. 

6. Bowen Wang^#, Xiaolin Liu^#, Zhenxiang Li^*#, Kang Zeng, Jiangyi Guo, Tongxu Xin, Zhen Zhang, Jian-Feng Li, Xueyong Yang^*. A nuclease-dead Cas9-derived tool represses target gene expression. Plant Physiology, 2024, 195: 1880–1892.

7. Yanling Wang^#, Zhaonian Dong^#, Yalin Ma, Yi Zheng, Sanwen Huang^*, Xueyong Yang^*. Comprehensive dissection of meiotic DNA double-strand breaks and crossovers in cucumber. Plant Physiology, 2023, https://doi.org/10.1093/plphys/kiad432.

8. Zhen Zhang ^#, Bowen Wang ^#, Shenhao Wang ^#, Lin Tao, Li Yang, Zunlian Zhao, Zhonghua Zhang, Sanwen Huang, Yang Xueyong^*. Genome-wide Target Mapping Shows Histone Deacetylase Complex 1 Regulates Cell Proliferation in Cucumber Fruit. Plant Physiology, 2020, 182:167–184.

9. Tongxu Xin^#, Tian Haojie^#, Yalin Ma^#, Shenhao Wang; Li Yang, Xutong Li, Mengzhuo Zhang, Chen Chen, Huaisong Wang, Haizhen Li, Jieting Xu, Sanwen Huang, Xueyong Yang^*. Targeted creation of new mutants with compact plant architecture using CRISPR/Cas9 genome editing by an optimized genetic transformation procedure in cucurbit plants, Horticulture Research, 2022, 9: uhab086. 

10. Xin Liu^#, Shuai Wang^*, Kang Zeng, Wenjing Li, Shenhao Wang, Sanwen Huang^*, Huasen Wang^*, Xueyong Yang^*. N-myristoyltransferase1 regulates biomass accumulation in cucumber (Cucumis sativus L.). Journal of Integrative Agriculture, 2025, 24(5): 1754–1768.

科研项目(近五年)

1. 国家自然科学基金优秀青年科学基金项目“蔬菜器官形成和发育的遗传基础与分子机制”， 2020.1-2022.12，130万元。

2. 国家自然科学基金面上项目“黄瓜果长关键基因Fld的群体遗传学和分子调控机理研究”， 2022.01-2025.12，58万元。

3. 国家重点研发计划课题“经济作物重大品种和骨干亲本形成的遗传基础”， 2021.12- 2026.11，425万元。

4. 国家重点研发计划课题“人工合成农作物的应用示范与田间效能评价”，2020.01-2024.12，192万元。

5. 北京市科技计划项目课题“主要果菜高效基因编辑技术体系建设及优异新种质创制”，2023.9-2026.8，400万元。